CPK ISOENZYME ELECTROPHORESIS

Creatine Phosphokinase activity is found in skeletal muscle, myocardium and brain as isoenzymes MM, MB and BB. Elevated levels of MB occur 4 to 6 hours after the onset of pain in myocardial infarction, peak at 18 to 24 hours and persist upto 72 hours. BB isoenzyme increases in patients with head injury and in some malignancies.