CREATININE, SERUM

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Creatinine is the product of creatine metabolism. It is a measure of renal function used for Diagnosing and monitoring treatment of acute and Chronic Kidney Diseases (CKD). KDIGO Clinical Practice Guidelines recommend clinical Laboratories should report estimated GFR (eGFR) in addition to the serum creatinine concentration in adults. It is considered as the best overall index of kidney function in health and disease. Estimated GFR is especially important in patients with CKD for monitoring and to identify disease at early stage in those with risk factors for CKD (diabetes, hypertension, cardiovascular disease, and family history of kidney disease). Early recognition and intervention are important in slowing the progression of CKD and preventing its complications

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Creatinine is a chemical compound left over from energy producing processes in your muscles. Healthy kidneys filter creatinine out of the blood & it exits your body as a waste product in urine. Your doctor prescribes this test if you have signs or symptoms of kidney disease; to screen for kidney disease if you have diabetes, high blood pressure or other conditions that increase the risk of kidney disease; to monitor kidney disease treatment; to monitor for side effects of drugs that may affect kidney function & to monitor if you have had a kidney transplant.

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