HIV 1 GENOTYPING & DRUG RESISTANCE

The high replication rate of HIV 1 coupled with its rapid mutation rate leads to accumulation of mutations, some of which reduce susceptibility to antiretroviral agents. HIV 1 Genotyping identifies mutations in HIV 1 Reverse Transcriptase & Protease genes. Genotyping helps in identifying the mutations associated with resistance and guiding initiation or change of Anti HIV 1 treatment regimens.