TISSUE TRANSGLUTAMINASE (tTG) ANTIBODY, IgA

This assay is useful in evaluating patients with Celiac disease including those with compatible symptoms, atypical symptoms and individuals at increased risk like positivity for HLA DQ2 / DQ8. It is also used as a screening test for Dermatitis herpetiformis. The test monitors adherence to gluten free diet.Test sensitivity increases from 91.5% for tTG IgA antibody alone to 98.5% when both IgA and IgG results are considered.