VITAMIN B12; CYANOCOBALAMIN

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Vitamin B12 is necessary for hematopoiesis and normal neuronal function. B12 deficiency may be due to lack of intrinsic factor secretion by gastric mucosa (gastrectomy, gastric atrophy) or intestinal malabsorption (ileal resection, small intestinal diseases) leading to Macrocytic anemia. This assay is useful for investigating Macrocytic anemia and as a workup of deficiencies seen in Megaloblastic anemia.

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Vitamin B-12 plays an important role in red blood cell formation, cell metabolism, nerve function & production of DNA that carries information about our genes. Food sources of vitamin B-12 include poultry, meat, fish and dairy products. People who follow a vegetarian or vegan diet might be prone to deficiency because plant foods do not contain vitamin B-12. Deficiency of vitamin B-12 can lead to anemia, fatigue, muscle weakness, intestinal problems, nerve damage and mood disturbances. Vitamin B-12 supplements are recommended during pregnancy, breast feeding & in vegetarians.

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